Autoimmune Disease Blog Diseases and Disorders fermented cod liver oil Grant Genereux Inflammation Nutrition Supplementation vitamin A vitamin A depletion diet

Vitamin A: Vitamin or Villain?

180DegreeHealth, from the start, has been about two main things:

  1. Slaying widely-held nutritional myths
  2. Figuring out what the hell is causing an accelerated improve in almost all health problems worldwide over the past century, the final 40 years particularly, and determine how greatest to turn these developments “180 degrees.”

Admittedly, 180D has finished much more of #1 than #2. The truth is, as a result of the pursuit of #2 attracted so many excessive health fanatics and disordered eaters, I felt obligated to principally drop the latter and shout “EAT AN EFFING SLICE OF PIZZA AND RELAX” from the rooftops.

Nevertheless it’s scary out there individuals. For instance, in simply 40 years, the Alzheimer’s fee in 75-85 yr olds in North America increased by 4,000%. Many other inflammatory and degenerative illnesses have seen increases almost as scary in that time interval. We will’t simply hand over as a result of some of our failed excessive eating regimen experiments didn’t work out. We’ve acquired to determine this out.

And so, I current to you in the present day a very great lead about what is perhaps inflicting all this, something which may probably slay THE most sacred nutritional cow, and something which may have real potential to reverse the horrifying current well being developments.

Have in mind, that is principally only a principle. Most theories are utterly flawed. A only a few are even partially right. I’m not 100% convinced about it, and you shouldn’t be either. You shouldn’t be 100% satisfied about anything in science. Nothing is ever set in stone, and one new discovery can dramatically upend the whole lot that has come before it.

What’s the idea?

The idea is that extra accumulation of Vitamin A in the body is the first explanation for body-wide irritation. This inflammation is invoking an immune response, and the immune response itself is doing much more injury on prime of it (by way of autoimmunity, principally).

Sounds fairly preposterous upon first look. I imply, we’re speaking about Vitamin A right here. You recognize, the FIRST VITAMIN ever discovered. It’s a substance present in virtually each food. The most typical type of vitamin A is retinol, and is used on the attention, hence the identify (retinol as in retina).

However it starts to sound quite a bit less preposterous once you consider it like this…

There was a huge improve in most inflammatory and immune circumstances during the last 40 years. So what modified significantly 40 years in the past and continued to get worse?

Nicely, there’s the low-fat weight-reduction plan craze. There’s the change to high fructose corn syrup. We started enjoying video games and utilizing computers. We began using a hell of a lot more chemical compounds, additives, and flavor enhancers in meals.

Those sound dangerous, and most pin the blame such things while not having to see a lot evidence, but there’s not likely a lot of a principle that one can build about how those issues trigger such a tidal wave of irritation and the immune system principally going apeshit as well.

The rise in vitamin A consumption, nevertheless, is rather more compelling. Proper according to the dramatic rise in illness was a dramatic rise in vitamin A consumption.

  • Right around 1980 the U.S. began pumping supplemental vitamin A into milk, breakfast cereal, toddler formulation, margarine, and other meals. Different nations adopted go well with.
  • Using vitamin A-loaded multivitamins absolutely skyrocketed (over 50% of U.S. citizens take a vitamin A-laden multivitamin every day)
  • The skin cancer scare began, and everybody began lathering themselves with sunscreen–wealthy in vitamin A palmitate.
  • Pimples lotions chock filled with vitamin A (I used to use prescription Retin-A) have been squirted on every pimpled face, later adopted by the notorious vitamin A-based Accutane

But that’s not all!

The consumption of foods rich in plant-sourced vitamin A (as carotenoids) went wild! International tomato consumption more than doubled. Yr-round recent fruit and vegetable availability elevated dramatically. The boon in wholesome vitamin (attempts at it, a minimum of) elevated wildly. Fruit and vegetable juice consumption skyrocketed. I mean, hardly anybody knew what a smoothie was in 1980. In 2005 I heard a kid as soon as say, “Who the hell eats a smoothie for breakfast?” The 2018 reply to that question is in fact, “EVERYONE!”

And then in fact there’s salads. And kale. KALE! Yes, humans have truly been making an attempt to eat it for years now.

Okay, I feel we will all agree that the consumption of vitamin A has gone approach up over the previous 40 years. Now, why the hell is that a dangerous thing?

So, definitely you’ve heard one thing along the strains of “taking too many vitamins can be bad.” Yeah, REAL dangerous. Vitamin A is by far the vitamin with the worst status relating to getting an excessive amount of of it. The listing of symptoms you will get from taking an excessive amount of vitamin A is a mile long, and doesn’t sound very pleasant.

That’s an acute situation, and may be easily and shortly fastened by going again to relatively regular vitamin A consumption ranges.

The idea put ahead by Grant Genereux is that vitamin A, a fat soluble vitamin, is stored away within the liver. The liver does NOT have limitless storage capability for vitamin A, so when the liver turns into saturated with it, it will get stored as retinoic acid (a nasty, inflammation-inducing substance used for chemotherapy and acid peels and the like) everywhere in the physique–the place it turns into a trigger for irritation and a belligerent response from the immune system.

Once you reach that time of saturation, all the vitamin A you ingest is a potent “poison.” Grant believes that the illness patterns seen worldwide, and the sudden rise, has all of the markings of a poisoning, not of a degenerative illness course of:

Does it not make some intuitive sense that whatever is inflicting these illnesses; it just needs to be something pervasive, but delicate, in our surroundings? One thing that is so apparent that it’s being ignored and ignored. One thing so little and virtually trivial, that it’s by no means too much of a suspect. One thing that is proper underneath our noses. One thing we’ve been informed, and we assume, is sweet for us. Yet, it’s one thing that can have a profound, and devastating impact on the human body.

Additionally, once you understand that the basis explanation for the autoimmune illnesses, and most of the mental well being issues, is a poisoning, you’ll perceive why all the varied medicine are completely ineffective. Or perhaps this vitamin A subclinical toxicity shouldn’t be obvious? In any case, this can be a very delicate and tough state of affairs that develops slowly over an extended interval. It’s more or much less documented to be massively unlikely to occur on as broad a scale as it is. But it’s occurring, simply with principally small or subclinical quantities of this potential toxin accumulating in the fallacious locations within the human body.

Simply to be clear here, this isn’t in any respect basic hypervitaminosis A. No, it’s far worse because the saturation levels are larger. I feel it’s insidious Vitaminosis A. This can be a very sluggish build as much as near saturation and thereafter remaining in a state of persistent delicate overflow of what now becomes a toxin. This process is so nicely documented and clinically confirmed, that I feel we will think about it to be an absolute reality. Earlier on I requested what might probably cause the top to toe self-destruction of the human body that we see with the autoimmune illnesses. Now we know; it’s truly a well-proven, and well-documented reality too. It’s retinoic acid.

How might a “vitamin” be inflicting all of this?

Properly, in Grant’s second e-book, Poisoning for Revenue, he does a reasonably damn good job of breaking down the issues within the unique experiments that identified this substance as the very first “vitamin.” It might not truly be a vitamin in any respect, but merely a standard poisonous substance present in meals that our livers normally maintain beneath containment, and that our bodies have discovered the right way to use over generations (for instance, vitamin A is released from the liver to struggle infections. It really works since, you recognize, it’s poison!). As most of you vitamin nerds know, liver is by far probably the most concentrated source of vitamin A, and is considered by most nutritionists to be a superfood. (Cod liver oil has virtually a spiritual following in circles like The Weston A. Worth Foundation, however many have gotten burned by consuming too much of it. Like, actually burned.)

Grant also purchased some gerbils and fed them a zero vitamin A weight loss plan with no sick impact. Quite the opposite. Awww, take a look at those cute lil’ fuckers! Reminds me of my two gerbils back in the day, which I named Koko B. Ware and Leapin’ Lanny Poffo, as a result of I’m the awesomest at naming stuff.

Some frisky gerbils that outlived the supposed vitamin A poor lab animals in experiments almost 100 years ago is mildly reassuring at greatest though. What about people?

Grant has been avoiding all sources of vitamin A 100% for almost 4 years I consider. Still kicking. Nonetheless capable of see. The truth is, he reversed a mile-long laundry listing of great, debilitating health issues doing so (eczema, weight achieve, and dementia most notably), and even had most of his grey hair turn again to brown in his 50’s.

The Andersen household has prevented vitamin A for 17 years as of this photograph (mother and father aged 44 and 57 within the photograph). Even the youngsters have hardly had a trace of vitamin A in their complete lives. Man, they’re actually in tough shape! They haven’t any eyes! 🙂

Vitamin A is meant to be a key nutrient for skin well being. Sorry woman, I need to see more of your skin. For science in fact!

dnk3tlkv4aeqjseNotice, Charlene “lizard skin” Andersen has famous her health issues (bronchial asthma, eczema, Lyme disease, and others) are rekindled by consuming liver, which she grew up eating regularly and having a robust affinity for.

Enough of that. Suffice it to say that there’s a LOT extra to the vitamin A narrative.

While most will just assume that Grant healed himself of his issues by eradicating all allergens (since he whittled his eating regimen right down to just some meals), or PUFA (he consumed hardly any in his weight loss plan as properly)–or simply flat out dismiss it as a result of he’s an engineer so subsequently couldn’t probably know his ass from a gap in the wall–I guarantee you there’s extra here than that. Once more, the idea shouldn’t sweep you off your ft and turn you into a zealot overnight. However it’s one thing to be open to.

As Grant states on the finish of his first e-book, Extinguishing the Fires of Hell:

“However, even with all this evidence, I’m not asking you to simply believe that this theory is correct. I’m only asking you to believe that it is quite possible for it to be correct. Whether it is correct or not is still an open question. The responsible answer to that question is that we really don’t know just yet. The great part of this investigation is that you now have an opportunity to help prove it one way or the other. We need more evidence, and a lot more results to prove it correct or not. The quickest way to get that evidence is for more people to apply this simple little diet experiment and report their results. I wish I could say the results will be fast and easy, but they will not be. This process will take time. I expect somewhere around three to twelve months, or longer for most adults. Therefore, we need to be both patient and diligent. Additionally, we need to be very careful not to jump to conclusions. This is serious business, deadly serious business. Please don’t report false results. Don’t report wishful thinking. I’d view doing so to be completely amoral and regarded as fraudulent. Also, please report all results. Both failures and successes need to be reported. For eczema, psoriasis, lupus, and most other autoimmune diseases, please post both before and after pictures.”

So what do you have to do with this info?

Properly, for starters I feel it might be safer to avoid vitamin A-laden supplements, together with cod liver oil, and fortified foods (milk and breakfast cereal being the worst), till we now have more info. We must be SURE that this stuff are useful and not dangerous before consuming them willy nilly. Thanks but no thanks for not diligently doing all of your homework earlier than implementing nation-wide dietary modifications, authorities! (grumbles, feels slight remorse over burning that Ron Paul poster a number of years again).

Additionally, like I have advisable since all the time, it is best to use shirts and hats as sunscreen, not white goop filled with vitamin A. Vitamin A makes the pores and skin tremendous sensitive to sunlight. I ended using it as a result of I received uninterested in getting horribly burned in minutes once I forgot to place it on, even with a darkish tan. As Grant factors out in his guide, slathering vitamin A cream on rodents causes pores and skin most cancers. Not an INCREASE in most cancers charges. 100%. Each. Single. One. Even with out daylight.

That’s what you need to do in case you’re healthy. That may hold your vitamin A intake doubtless inside the boundaries of what your liver can cope with, and hopefully you gained’t run into long-term problems.

You also needs to hold your liver healthy and highly metabolically lively. There are numerous elements concerned in liver well being and performance, but a pair no brainers are preferentially opting for saturated fats over unsaturated fats (to assist avoid fatty liver disease), and maintain your metabolism excessive. The liver is among the most metabolically lively tissues within the body, and its metabolic exercise slows dramatically to lower metabolic fee if you end up overstressed and/or undernourished (calorically). This is maybe why stress and a lowered metabolism may cause autoimmune flareups, and interventions that increase metabolism and alleviate stress are so efficient. For a while no less than.

For those who’re sick and overrun with an autoimmune disease or other inflammatory, supposedly “incurable” situation, properly hell, give a Vitamin A-depleted weight loss plan a whirl. What have you ever acquired to lose, actually? I feel this “Villain A” concept is promising sufficient to discover.

How does one deplete themselves of vitamin A? Consuming none of it for 7 months or so should do the trick, if Grant’s estimates are right. The food plan is brutally restrictive, restricted principally to grains (he used rice), white greens (assume peeled white potatoes, turnips, celeriac, parsnips, jicama, cauliflower), beef, and raisins and grape juice. However it beats eating only beef, which seems to be all the fashion lately with regards to toppling autoimmune circumstances and psychological issues.

Observe, a food plan of beef and water only incorporates no vitamin A. Coincidence? Determine for your self.

We’ll talk about this more on an ongoing foundation for positive. To greatest participate in discussions, I like to recommend studying Grant’s two books HERE and HERE.

And in addition reading by means of the lengthy and extremely contentious thread on the Ray Peat discussion board about it HERE. Franko solutions questions about it and debates with extra power than I might ever muster, so I might undoubtedly examine that out.

And naturally read the comments right here! I’m positive there might be at the very least a number of hundred.

Chart put collectively by 180D reader Jeanne of vitamin A content material of widespread meals.

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